Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract
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چکیده
منابع مشابه
Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract.
BACKGROUND Pro-inflammatory chemokines that attract and cytokines that activate immune cells contribute to normal physiological homeostasis in the female reproductive tract, and are needed to deal effectively with potential pathogenic microbes. Mucosal epithelial cells are capable of producing these factors that communicate with cells of the innate and adaptive immune systems. METHODS Epithel...
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Trichomonas vaginalis is one of the most common nonviral sexually transmitted human infections and, worldwide, has been linked to increased incidence of human immunodeficiency virus type 1 transmission, preterm delivery, low birth weight, cervical cancer, and vaginitis. The molecular pathways that are important in initiating host inflammatory and immune responses to T. vaginalis are poorly unde...
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BACKGROUND Chronic interstitial scarring contributes to the progression of renal failure in glomerular disease but its cause is unknown. The development of proteinuria could stimulate tubular cells to release cytokines, chemoattractants and matrix proteins into the interstitium, thus contributing to interstitial disease. METHODS Polarized human tubular epithelial cells were grown on permeable...
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Cytokines and chemokines are released from a wide range of immune cells, and are essential for the communication of signals in both innate and adaptive immunity. While there is a substantial body of literature regarding the function of cytokines and chemokines in immunity, remarkably little has been done to determine how these are packaged and secreted from a range of immune cells. Our knowledg...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2005
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/deh806